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This monoclonal antibody recognizes a 100kDa glycoprotein, CD10. CD10 is also known as MME and Common Acute Lymphocytic Leukemia Antigen (CALLA). CD 10 has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides. It is a type II cell surface glycoprotein typically expressed on acute lymphoblastic leukemias (ALL). In normal healthy volunteers precursors of B and T cells and granulocytes also express CD10. CD10 plays important role in the development process of B cell in germinal centers.
Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of REH cell line such that 0.5μg (unconjugated, Biotin) or 5μl (conjugated) of these products are sufficient for staining 1 million cells in a 100μl staining volume or 100μl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.